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The upper and lower parts of your anus (above and below the pectinate line) have different vascular supply and nerve supply. This is why your anus is much more sensitive to pain and other sensations below the line (in the lower two-thirds). Your internal and external anal sphincters also have a different nerve supply, which is why the inner one is involuntary (out of your control) and the outer one is under voluntary control.

Anal sex, like any kind of sex, can be perfectly safe if you take the correct precautions. According to the CDC, you may be more vulnerable to contracting STIs or HIV if you have anal sex as the is more prone to damage that can open you up to infection. This risk is higher for the person receiving anal sex, though the person giving it can also be affected. To decrease that risk, it’s imperative that you use both , according to Planned Parenthood, because the anus, unlike the vagina, doesn’t provide natural lubrication. A silicone-based lube will provide the necessary and is with condoms.

If you regularly engage in anal sex, with gay or bisexual men who are not monogamous, you might also consider taking — pre-exposure prophylaxis. PrEP is a drug that can your risk of contracting HIV. If you have had unprotected anal sex and you’re concerned that you were exposed to HIV, you can ask your doctor for (post-exposure prophylaxis) within 72 hours of the potential exposure, which may reduce your risk of contracting HIV. It’s important to note that neither PrEP or PEP protect against other STIs, so it’s still important to use a barrier form of protection.

Anal sex can feel great, which is why many people include it as a regular part of their sex life. But notes that anal sex can hurt if you’re not relaxed or if you don’t use lube. As we explain below, it’s not something you should jump into without a little preparation. using plenty of lube and starting by inserting smaller things (like a finger) into your anus, then working up to bigger things (like a penis) can lessen the pain. You should also keep an open flow of communication during partnered anal sex so you can tell your partner how fast or slow they should go, if you need more lube, what feels good, and anything else that’s on your mind. Great communication can help you have a more pleasurable experience.

Condoms are also nonnegotiable. There is no risk of pregnancy during anal sex, but STIs are widespread and abundant. Protect yourself and practice safe sex every single time.

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